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The Department of Oncology at Amala Hospital started in 1978is one of the first cancer centres in Kerala. The Radiation Oncology department initiated its work with 3 cobalt teletherapy machines and later upgraded with 2 linear accelerators (UNIQUE in 2013 and TRUBEAM in 2023) and brachytherapy. The programs offered by the department are of international standards with advanced Clinical Radiation Therapy techniques and treatment. The department comprises of a dedicated team of doctors, highly trained and qualified medical physicists, radiation technologists, well trained oncology nurses, and supportive care team members. The department has been accredited by NABH, and it strives towards ensuring a patient-centred, cost-effective and high quality of comprehensive radiation treatment. 


  •   Linear Accelerators are used for external beam treatment of tumors. The Department has the latest Linear Accelerator Truebeam with HD120-MLC v2.7, state of the art, premium end, high dose rate, delta couch with 6 degrees of freedom movement. Installed in 2023, the first of its kind in Kerala, it uses Artificial intelligence incorporated treatment software which enhances treatment precision. 

  • Installed in 2013, UNIQUE by the Varian allows us to perform various treatment techniques including 2D and 3D radiation therapy, IMRT and RapidArc. 

  • Besides external radiation treatments, in-body treatments (Brachytherapy) are also performed. In our center, GAMMAMED PLUS HDR installed in 2012, in which in-body treatments are performed, is a brachytherapy device. Brachytherapy is used in the intra-cavity or intra-tissue radiation therapy of uterine, esophagus and bronchial tumors. The radio-active source Iridum-192, is placed in the space or tissue using applicators and treatment is delivered. Dose calculations are made in the ECLIPSE Treatment Planning system and then radioactive material is loaded from outside. 

  • Treatment Planning System
  •  TPS comprises of computers and software programs which are the key to improved patient outcomes. Once image datasets are loaded and the tumors are identified, the systems develop a complex plan quickly and accurately on how the system will deliver radiation. The software computes the expected dose distribution in the patient’s tissue. These systems also help navigate beam placement based on avoiding critical structures. These tools are essential for precise treatment delivery. 

  • Dedicated CT Simulator
  • CT simulators have become the standard of care for radiotherapy.  Our department has the Optima CT 550, which is a 16 slice dedicated CT simulator. It is a real-time, CT-linked, 3-D treatment planning system, which consists of a CT scanner, a multi-image display, a treatment planning device with real-time visual optimization, and a laser beam projector. 


Facilities are available on all working days (Monday – Saturday) from 8:00 am to 4:00 pm. 

Day care chemotherapy.

Radiotherapy treatment and planning services on all working days (Monday – Friday) and on Saturdays in case of emergency. 

Together with the nursing and supporting staff, we offer in-patient services to those who need intensive care during or after Radiation Therapy. Services are also provided to patients who wish for hospital stay during the course of treatment or those who require Chemotherapy.We also have 24x7 Oncology ICU service for those who need critical care with highly trained ICU nursing and supportive staff.

Highly precise technique that allows delivery of high dose radiation to conform to small tumors in a very short period of time.

Treats both benign and malignant brain and spine tumors.

To treat tumors in chest, abdomen or pelvis that cannot be removed surgically or treated with conventional Radiation Therapy.

It involves using very secure immobilization of the head or body as well as using techniques that allow the radiation beam to account for organ motion during treatment.

Our first SBRT to the Liver was successfully done in January 2023 .

External beam radiation therapy that can be completed in 1 to 5 treatments, with extreme accuracy, minimizing the effect on adjacent critical organs. 

Suitable for small-well defined tumors.

Advanced imaging modalities with in-room imaging facilities to adjust for tumor motion or patient setup accuracy between treatments. This allows for more accurate delivery of radiation. We use 2D based kV and MV imaging or 3D based Cone Beam CT. This technique is used for prostate, lung, breast malignancies as well as SRS, SBRT. 

Advanced radiotherapy technique which uses inverse planning and dose calculation while delivering highly conformal radiation. The radiation beam is broken up into many beamlets and the intensity of each beamlet can be adjusted individually. It safely allows a higher dose of radiation for improved tumor control with significant sparing of organs at risk. 

Successful treatment outcome in radiation oncology is based on irradiation of tumor-bearing tissues to adequate, or curative doses; and the sparing of normal, or uninvolved, tissues from unnecessary radiation. The radiation beams can be precisely tailored to the size and shape of the tumor using MLCs. 

Time-tested and reliable radiation technique; cost-effective.

Most often used for palliative intent Radiotherapy .

Management of primary malignant bone tumors of the extremity has changed dramatically over the last few decades. Amputation has been replaced by limb-conservation therapy. One approach for limb reconstruction is reimplantation of the tumor bearing bone following extracorporeal irradiation. Here the tumor bearing bone segment is resected, treated with a single fraction of radiation therapy extracorporeally and re-implanted with fixation devices. ECI is done in collaboration with the Department of Orthopaedics.

As part of conditioning regimens for acute leukemia and to deliver organ spared targeted Radiotherapy in those undergoing Hematopoietic cell transplantation 

More targeted forms of Radiotherapy which have the potential to decrease toxicity and escalate the dose to the entire body bone marrow

Radio-active source (Iridium-192) is placed within the body cavity or tissue using applicators and radiation is delivered.

Brachytherapy is suggested for Endometrial Malignancies as day care procedure. The treatment takes about 5-15 minutes. 

Brachytherapy for cervical malignancies are done under short GA, for whom IP services are provided. The treatment schedule which includes 3 applications is completed in 1 week time. 

Majority of the cases dealt by the Radiation department at Amala IMS are Endometrial, Cervical and Vaginal Malignancies. Our physicians also have expertise in Endobronchial Brachytherapy. 

 PG Training

 MD program was started in 2017. The department has an annual intake of one PG resident for the course of MD Radiation Oncology (duration 3 years). As per NMC regulations,  patient-oriented course with experience in outpatient and inpatient care, planning and execution of treatment, Brachytherapy and chemotherapy training, is offered. Academic training sessions include Radiation Oncology lectures, Radiation Physics classes, regular journal clubs, case presentations and discussions. PGs are also posted in various departments such as Nuclear medicine, Radiology, Medical Oncology, Surgical Oncology, Pain and Palliative Care, ENT and Pathology. 

 UG Training

As per curriculum, UG residents are posted for a 1 week period during their 2nd year of MBBS and internship. They are offered training in basic knowledge in Oncology, along with OP and IP care. End posting exams, which include case presentations and discussions and role play are conducted on a regular basis.   

DRT Training, M.SC. Oncology

 Regular classes, hands on experience and training are provided on patient care, Radiotherapy treatment techniques, with regular exams being conducted. 


Dr. Jomon Raphael C

Professor & HOD

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Dr. Mathew Varghese K

Associate Professor

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Dr. Rajkrishna B

Assistant Professor

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Dr. Febin Antony

Assistant Professor

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Dr. Abney Sara Abraham

Senior Resident

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Dr. Jamuna Angel Joy

Senior Resident

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CME Details Date of Conduct
Name : CME
Theme/Subject : Multidisciplinary Gynecological cancer CME

Name : CME
Theme/Subject : Amala Oncology Breast Cancer Conference



  • Jomon C Raphael, Mathew K Varghese, Paul G Gopu, K Venkatesan, AD Jimson, Antony Febin. Effectiveness of abdominal compression in reducing internal target motion during conformal radiotherapy for carcinoma stomach – A pilot study- Indian J Cancer 2018 | Volume : 55 | Issue : 3|Page : 226-229.
  • K.Venkatesan, C.J.Raphael, K.M.Varghese, P. Gopu, S.Sivakumar, M.Boban, N.A.N. Raj, K.Senthilnathan, P.Ramesh Babu; Int. J. Radiat. Res., July 2020 18(3:557-569) Volume and dosimetric analysis of rectum and bladder for prostatic carcinoma patients by using kilo voltage cone beam computed tomography (CBCT)
  • K., Varghese, Raphael Jomon C., Antony Febin, Mohan Malini, & Gopu Paul. "Efficacy of vaginal dilator use in preventing vaginal stenosis among cervical and endometrial cancer patients underwent radiotherapy." International Journal of Research in Medical Sciences [Online], 9.4 (2021):1034-1042. Web. 15 Jul. 2021
  • Antony F, Chalissery JR, Varghese KM, Gopu GP, Boban M. Relationship of irradiated bone marrow volume and neutropenia in patients undergoing concurrent chemoradiation therapy for cervical cancer. Journal of Cancer Research and Therapeutics. 2022 Oct 1;18(6):1498-503.
  • Antony F, Raphael JC, Varghese MK, Gopu P. Oropharyngeal carcinoma in fanconi anemia patient-Radiation treatment, toxicity, and a year follow-up: Case report. Indian Journal of Cancer. 2021 Jul 1;58(3):434-6.
  • Chalissery JR, Jose TA, Pillai S, Unni H, Varghese KM, Gopu GP, Venkatesan K. Clinical impact of adjuvant chemotherapy and radiation for carcinoma stomach: Experience from a tertiary care center. Journal of Cancer Research and Therapeutics. 2020 Dec 1;16(Suppl 1):S122-7.
  • Kaliyaperumal V, Raphael CJ, Varghese KM, Gopu P, Sivakumar S, Boban M, Raj NA, Senthilnathan K, Babu PR. Study of variation in dose calculation accuracy between kV cone-beam computed tomography and kV fan-Beam computed tomography. Journal of Medical Physics. 2017 Jul;42(3):171.
  • Chalissery JR, Sudheeran PC, Varghese KM, Venkatesan K. Radical chemo-irradiation using intensity-modulated radiotherapy for locally advanced head and neck cancer in elderly patients: Experience from a tertiary care center in South India. Indian Journal of Cancer. 2016 Oct 1;53(4):483-6.
  • Raphael JC, Ram TS, Pavamani S, Choudharie L, Viswanathan PN. Squamous cell carcinoma cervix with metastasis to pyloroduodenal region. Journal of cancer Research and Therapeutics. 2011 Apr 1;7(2):183-4.
  • C JR, I R, B R, B S, John S.Feasibility and Response of Concurrent Weekly Docetaxel with Radical Radiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma.J Clin of Diagn Res.2015; 9(3):XC01-XC04.
  • Babu N, Saikumar C, Chalissery JR, Kumar H.Extracellular Enzymatic Activity of Candida Species Isolated from Patients with Head and Neck Cancer Undergoing Radiation Therapy and Its Correlation with Mucositis: A Cross-Sectional Study J Clin of Diagn Res.2023; 17(9):DC01-DC05.
  • Babu N, Saikumar C, Chalissery JR.A Study on Subsite-specific Prevalence of Candidiasis in Head and Neck Cancer Patients and its Antifungal Susceptibility Pattern: A Cross-sectional StudyJ Clin of Diagn Res.2023; 17(10):DC09-DC13.
  • Neethu B, Chitralekha S, Jomon Raphael C. Mechanisms of Azole Resistance in Candida- A Narrative Review. Int J Cur Res Rev. 15(20), November, 2023, 05-12,
  • Chalissery JR, Jose TA, Pillai S, Unni H, Varghese KM, Gopu GP, Venkatesan K. Clinical impact of adjuvant chemotherapy and radiation for carcinoma stomach: Experience from a tertiary care center. J Cancer Res Ther. 2020 Dec;16 (Supplement): S122-S127.
  • Mathew Varghese K, Geeta S. Narayanan, Bhaskar Vishwanathan, Shashidhar V. Karpurmath, Soumya Narayanan. Comparison of altered fractionation schedule with concurrent chemo-radiation for squamous cell carcinoma of head and neck. International Journal of Research in Medical Sciences| August2020| Vol 8| Issue 8| Pages: 2834-2838| pISSN2320-6071.
  • Varghese Mathew K, Raphael Jomon C, Antony Febin, Mohan Malini, Gopu Paul. Efficacy of vaginal dilator use in preventing vaginal stenosis among cervical and endometrial cancer patients underwent radiotherapy. International Journal of Research in Medical Sciences| April 2021| Vol 9| Issue 4| Pages: 1034-1042| pISSN 2320-6071.
  • Rajkrishna, B., Rajesh, B., Patricia, S., & Selvamani, B. (2020). “Patterns of recurrence in patients receiving conformal radiation for intracranial meningioma: A single-institution experience”. Journal of Radiotherapy in Practice, 1-7.
  • Balakrishnan, Rajesh, Patricia Sebastian, Rajkrishna B, Jeyaanth Pulivadula Venkatasai, and Selvamani Backianathan. (2020). “Radiotherapeutic Management of Brain Tumors during the COVID-19 Pandemic.” Journal of Radiotherapy in Practice. Cambridge University Press, 1–4.
  • Rajkrishna B, Balakrishnan R, Raam M, Santhosh Raj A, Sebastian P, Selvamani B. Aggressive malignant phyllodes tumor of breast with omental metastases - A case report. Breast Dis. 2021;40(4):287-291. doi: 10.3233/BD-201054. PMID: 34420938.
  • Venkatasai J, Balakrishnan R, Rajkrishna B, Sebastain P, John RR, Vanjare HA, Prabhu K, Nair B, Mathew LG, Backianathan S. A pragmatic diagnostic approach to primary intracranial germ cell tumors and their treatment outcomes. CNS Oncol. 2021 Nov 22;10(4): CNS79. doi: 10.2217/cns-2021-0012. Epub ahead of print. PMID: 34806399; PMCID: PMC8610002.
  • Rajkrishna B, Das Saikat, Masih Dipti, Putta Tharani, Raghunath Rajat, Ram Thomas Samuel Ram.2022. “Magnetic resonance imaging downstaging, pathological response, and microsatellite instability status in patients with signet-ring cell carcinoma rectum undergoing preoperative long-course chemoradiation.” Current Medical Issues;An official publication of Christian Medical College Vellore Association:154-160.doi: 10.4103/cmi.cmi_23_2
  • Henry Finlay Godson, Jose Solomon Raj , Patricia Sebastian, Retna Y Ponmalar , Ebenezer Suman Babu , Ivin Paul, Raj Krishna, Selvamani Backianathan, Biju George, Paul B Ravindran, Rajesh Balakrishnan Feasibility study of total marrow lymphoid irradiation with volumetric modulated arc therapy: clinical implementation in a tertiary care center. Strahlenther Onkol. 2023 Jun 6. doi: 10.1007/s00066-023-02100-x. Epub ahead of print. PMID: 37278833.
  • Antony F, Dubey A, Skrabek P, Tsang LF, Lambert P, Bybel B, Ahmed N. Hypofractionated Radiotherapy for Hematologic Malignancies during the COVID-19 Pandemic and Beyond. Curr Oncol. 2024 Jan 10;31(1):383-393.
  • Soliman Y, Antony F, Vivian M, Venkatraman S, Nashed M. Cardiac migration of an implanted hepatic fiducial marker used for stereotactic body radiation therapy - A case report. J Cancer Res Ther. 2024 Jan 22.
  • Antony, F; Chalissery, Jomon Raphael; Gilvaz, Sareena1. Radiotherapy for successful symptom control in recurrent refractory endometriosis: A case report. Journal of Cancer Research and Therapeutics. April 30, 2023.
  • Antony F, Chalissery JR, Varghese KM, Gopu GP, Boban M. Relationship of irradiated bone marrow volume and neutropenia in patients undergoing concurrent chemoradiation therapy for cervical cancer. J Cancer Res Ther. 2022 Oct-Dec;18(6):1498-1503.
  • Pattiyeil A, Antony F, Cyriac SL, Jose A, P JM. Retrospective Analysis of Early Impact of COVID-9 on Systemic Cancer Treatment. Indian Journal of Medical and Paediatric Oncology 2021; 42(01):015-020.
  • Mathew VK, Jomon CR, Antony F, Paul G. Efficacy of vaginal dilator use in preventing vaginal stenosis among cervical and endometrial cancer patients underwent radiotherapy. Int J Res Med Sci 2021; 9:1034-42.
  • Antony F, Mathew VK, Jomon RC, Paul GG, Sivakumar S. Dosimetric comparison of organs at risk with three-dimensional conformal radiation, intensity-modulated radiation and volumetric-modulated arc therapy in cervical cancer: a case series. Int J Adv Med 2021; 8:586-90.
  • Gopu P, Antony F, Cyriac S, Karakasis K, Oza AM. Updates on systemic therapy for cervical cancer. Indian J Med Res. 2021 Aug;154(2):293-302.
  • Radhakrishnan S, Raju S, Joy JA, Ramakrishnan S. Histopathological subtypes of lung cancer presented at a tertiary care cancer hospital in Kerala: a cross sectional stud. Int J Adv Med 2021;8:11-5.